The Matsuno brothers try to adapt their show to contemporary times, with mixed results.

The Matsuno brothers struggle to find employment. Later, Osomatsu tries to take an interest in his brothers' lives but winds up being a nuisance to them.

This week's episode is the tidbits collection. Everything from Dekapan-man, to what happens if you try to horde your pachinko winnings, to a bath house quiz.

The Matsuno brothers compete to ensure their divorcing parents will care of each of them. Meanwhile, Totoko asks the brothers for help in a crisis.

Karamatsu gets kidnapped, but his brothers don't do anything. Later, a cat gets to speak and read minds, which causes mayhem for the Matsuno brothers.

The Matsunos are invited to Hatabou's birthday part. Meanwhile, Iyami discovers that his buckteeth contain a rare metal.

Todomatsu gets a job at a local coffeehouse. His brothers want no such success. / Dekapan and Dayon enjoy a carefree northbound trip together.

Captain Choromatsu invites an interesting detective onto an increasingly dangerous murder case to ease the tension of the crew. / Totoko wants to be a popular idol, but reality is so cruel.

Karamatsu ends up as Chibita's apprentice at his oden stand. Meanwhile, Jyushimatsu falls in love and his brothers try to help him achieve his romance.

Iyami and Chibita dress up as girls, and trick the Matsuno brothers into falling in love with them with the help of a sex-change drug. It's only a matter of time before this plan goes bad.

A series of Christmas-themed skits. Among those included are a zombified cold open, Ichimatsu disturbing a happy couple on a date, an F6 holiday fantasy, and the Annual Matsuno Family Christmas Gift Exchange.

Osomatsu and Totoko host an end of year special broadcast, looking back on previous episodes to determine which of the brothers is the biggest loser.

A salaryman named Sanematsu takes care of his six siblings, the Matsuno brothers play the roles of a friend group of working girls, and Choromatsu gets caught during a private moment.

The sextuplets catch a resilient cold. Later, the brothers question Todomatsu about all the things he hasn't told them about his personal life. Afterwards, Choromatsu plays a paranoid vice-principal overly worried about plans for his school's cultural festival.

Jyushimatsu goes to a job interview, proving to be a total nuisance for the interviewers. Later, the Girlymatsus return to go on a ladies' trip, causing trouble for each other as they arrive. After, Chibita falls in love with a fairy who manifested from a lonely flower.

At a cat cafe, Ichimatsu gets a job interview, but when in Rome, he does as the locals do. Later, in an apocalyptic world, F6 battles against Iyami and Dekapan, who are robbing the dry-skinned citizens of all of their lotion. After, Ichimatsu is forced to pretend to be Karamatsu after Osomatsu catches him trying on his clothes.

A series of Jyushimatsu-oriented skits, including the fifth-youngest defusing a bomb, having a late-night cup of noodles, selling baseball doujins at Comiket, and devolving the world into its written essentials.

Wanting to become the main protagonist of the franchise again, Iyami holds a bizarre kart race to determine who the protagonist of Osomatsu-san will be.

A series of skits take place, set during the Sengoku era. Back in the present, Choromatsu decides to quit being an idol-worshipper and pursue a job, with only his self-awareness standing in the way.

Hatabou starts his own catering service, cooking with a delicious mystery meat. Later, Osomatsu, Karamatsu, and the rest play delinquent high school students competing to see who's the toughest. Afterwards, Iyami starts a comedy class hoping to earn a quick buck.

On a rainy evening, the brothers play a fierce game of mahjong. Later, the brothers suddenly find themselves joined by a seventh brother, Kamimatsu, born from the goodness that fell out of the brothers' hearts.

Todomatsu holds auditions to take one of his brothers with him to a mixer, struggling to find anyone worth taking. Meanwhile, Iyami meets a kung-fu master who believes him to possess a special technique.

When the family heater runs out of kerosene, the brothers to force each other to get a refill. Meanwhile, Osomatsu, Karamatsu, and Choromatsu find themselves in an underground village populated by a tribe of Dayon people.

Totoko is jealous when those she knows find more success than her. Meanwhile, Choromatsu manages to land a job and moves out of the house, with the other brothers soon following suit, leaving just Osomatsu alone.

The brothers quickly abandon their new lifestyles upon learning they have been invited to a baseball tournament for the finale.

The 10-year-old Matsuno sextuplets of Osomatsu-kun are given a glimpse of the future and see they're going to get fat, greedy and beaten up by angry girls.

The brothers try their hand as streamers after being chastised by their parents for not having jobs. Later, Iyami uses an experimental detergent to keep his suit clean, but after being confused by the Matsunos as an expensive liquor, is revealed to turn anything invisible (up to a point).

Prehistoric versions of the brothers invent ways for them to relive any pent-up urges, with varying degrees of success. Later, Choromatsu and Ichimatsu struggle to make conversation with each other. After, Totoko takes part in an eating contest but keeps getting distracted by the brothers and guest star Shouei.

The prehistoric sextuplets return, partaking in dangerous sports. Later, in modern day, noticing their father acting strangely, the brothers discover that he is worried that there's not enough spark in his marriage. Feeling he should return to a more innocent time, the boys give their old man a masterclass in being a virgin, albeit with no success. After embarrassing himself in front of his sons, Matsuzou considers a love potion from Dekapan, but is this really the best way to patch things up with the love of his life?

A series of summer-themed skits. Jyushimatsu takes part in radio exercises, Iyami and Chibita try to beat the heat, Todomatsu keeps finding himself exiled by his brothers, Karamatsu tries to inject summer into everyone's lives, and the sextuplets attempt to talk to girls on the beach.

Iyami mooches off the sextuplets after falling on hard times and Hatabou searches for a friend.

The prehistoric sextuplets fool with nature for the last time. Several thousand years later, in a parody of Romance of the Three Kingdoms, Emperor Osomatsu and a group of bizarre generals attempt to take over the country. Meanwhile, in the real world, Osomatsu joins Todomatsu at a mixer, struggling to keep his perverted instincts in check.

Dayon uses Dekapan's latest invention to merge various people together into new beings, with a fiendish end goal in mind. Jyushimatsu becomes determined to get a job at a sea park as an actual dolphin, receiving strict training from a familiar female trainer. Meanwhile, Totoko and Nyaa encounter each other at Chibita's oden stand.

Ichimatsu struggles to get any sleep with his brothers being noisy all night and refusing to turn off the light. Unable to take anymore, Ichimatsu starts monitoring the brothers' courtesy towards each other, leading Osomatsu to get criticized the most. Later, Iyami proves his skills at the arcades by playing games at their highest difficulty.

Karamatsu tries to take on various requests from everyone to look like a reliable brother, only to take on more than he can handle, so Choromatsu tries to teach him how to refuse. Totoko begins working at a company, proving to be a handful for her superior Todomatsu. Later, a pair of seiyuu attend a dubbing session of an episode of Mr. Osomatsu, witnessing how the sextuplets do their work.

Already angered over the siblings gambling instead of paying off their oden tab, Chibita vows revenge on them after they pluck out his one-and-only hair. That night, Chibita begins taking out the siblings on by one, shaving all of their hair and stuffing oden in their bodies.

Jyushimatsu befriends a young boy named Eitarou but gets called in by Eitarou's mother when he starts imitating him. Later, Dayon steals Dekapan's underwear, forcing him to give chase all over the city and universe while butt naked.

A series of end-of-year skits. Osomatsu and Choromatsu try to do one thing that could make them say they had a good year. Ichimatsu gets persuaded to take part in a lottery, Dekapan and Dayon pound mochi together, Hatobou gets pestered by some greedy Jizou statues, and Choromatsu sends some untruthful New Years' cards. During the second half, a news crew documents Todomatsu, who was let go from the Matsuno family the previous year and is forced to try out for a reserve team.

Sanematsu wakes up in Osomatsu's world as the seventh Matsuno brother. Later, Jyushimatsu, Iyami, and Hatabou go on an expedition to find a Super Mongolian Death Worm. After, Choromatsu changes up his image by dying his hair brown, making it hard for his brothers to tell him that it's doesn't actually make him look cool.

The brothers struggle to remove the lid off of a particularly stubborn jar. After, Karamatsu runs his own taxi service, proving to have no idea what he is doing when he picks up an office lady played by Totoko. Finally, Totty holds a quiz for his brothers, containing several questions without right answers.

A group of aliens pursue the legendary space pirate, Shazarr. Later, displeased with Chibita's oden, Matsuzou serves up his own brand of the dish. Finally, the sextuplets become enamored by their new neighbor, Kinko Inuyama, prompting jealousy from Totoko when they go on a date with Kinko instead of her.

Ichimatsu becomes paranoid when lucky things happen to him all day, so he and Jyushimatsu try to punish themselves to balance things out. A lovey-dovey couple go to a hot spring inn that's haunted by a zashiki-warashi named Osoma.

In the 1960s, Iyami comes across a blind flower girl named Okiku and, despite being poor himself, tries to help her raise money for eye surgery.

After Dekapan becomes president, his secretary Todomatsu tries to keep him from pressing the Big Red Button. Iyami attempts to pull off a sham ventriloquism scheme by having Chibita and Hatabou act as his puppets. On Valentine's Day, the brothers try in vain to get some Valentine's chocolate from someone.

Yet another collection of random skits, with Dayon's live reaction complimenting. Chibita tries selling some sextuplet meat buns, Choromatsu files his taxes, Osomatsu accuses his brothers of stealing his wallet, a fierce wave of pollen hits town, Totoko tries to escape a creepy maze, raccoon Jyushimatsu cleans his food, Todomatsu tries doing something crazy, kindergartners visit a bread factory, the Proper-Rangers prepare to set off, and Osomatsu takes part in an Olympic skeleton event.

The brothers get rowdy while getting drunk at a restaurant. Unemployed office lady Totomi ends up taking a job at a strange establishment that offers some peculiar services. After being visited by a salesman, Matsuyo contemplates sending off one of her sons to a NEET correctional facility, asking Choromatsu to help her decide which one to send away.

Osomatsu and the rest take off for a wonderful Hawaiian vacation, only for disaster to strike, crashing Hatabou's private jet somewhere in the Pacific. How will our strange company survive the terrible desert island wilderness?

The Matsunos get drunk at the izakaya again. Dayon meets his doppelgänger. Iyami attempts suicide. The Matsunos get drunk at the izakaya one last time, but things turn introspective.

Matsuzou becomes hospitalized, leading the brothers to seriously think about their lives and get proper jobs to support their family. A chance meeting with Totoko sets Osomatsu's mind straight...

The Matsunos and Iyami are killed in a freak plane crash, sending them to Hell. In mourning, the others ponder a way to bring the status quo to its rightful place with the help of someone near and dear to them.