Earl tries to cross of number four off his list “Blew dad’s chance to be elected mayor”. Four years earlier, Carl Hickey ran for mayor to redirect a proposed airplane traffic route over his house and away from the wealthy part of town. Earl unfortunately ruins any chances of his father winning when caught in on tape assaulting a police officer. Earl must now help his father get elected and mend his relationship with his father.

It's Mother's Day again when Earl remembers that he has never given his mother a Mother's Day gift Just as he and Randy are about to finish carrying out his long overdue gift his mother decides her repayment should include Earl doing something for his father.

Earl tries to make amends with Tom (number 50), the older man they let be the lead singer in his band but then kicked out before their first performance. While trying to arrange a reunion show Earl must also deal with Number 51, "Slept with Ralph's mom."

Earl wants to use his birthday to look back on all the good he's done over the past year, but at his party, everyone seems to want to talk about his past misdeeds instead.

With Joy now pregnant again, Earl looks back on her pregnancy during their marriage, and how his father was responsible for one of his first truly good deeds.

After a car accident Earl is put in a coma and finds himself in an alternate world shown as a sitcom, while his friends try to keep him alive.

Nothing can get Earl out of his coma, so Randy turns to a young faith healer from their past. However, the boy says that he no longer heals people because he discovered how Earl lived his life after he "healed" him the first time.

When Randy visits his parents to make up for their ruined vacation, he realizes that he forgot to tell them about Earl's prison sentence and the following coma at all.

When Earl finds out that making up for all the bad things he did to women changes Billie's behavior to the good, he picks the worst thing he ever did to women on his list. Billie wants him to choose between her and his list. When he picks the list, she steals it and starts undoing the items he has already accomplished.

Earl and Randy decide it's time to make amends with their childhood neighbors, the Clarks. But when they discover more skeletons in the closet than they had expected, the brothers find themselves needing to sort out some family issues between their mom and dad. Meanwhile, Joy has duped one-eyed Willy out of his glass eye, and despite Darnell's efforts Willy may never "see" that eye again.